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If you aren’t losing weight with GLP-1 drugs, this may be one reason why - The Washington Post
Overview
A study linking variation in two gut-hormone genes to different responses to GLP-1 drugs explains part of why outcomes vary across patients, but lifestyle factors remain important. The new discovery that aging produces stem cells that seed belly fat suggests an additional, tissue-level reason some people gain abdominal fat or resist drug effects, and indicates non-hormonal targets could complement GLP-1 therapies. Combining genetic insights, medication choices, and individualized activity plans will improve tailored treatment strategies and research should examine how these stem-cell pathways interact with genetic subgroups.
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